# Amino Acids for low serotonin / dopamine etc **URL:** \ **Category:** Complementary Therapies\ **Created:** [August 23, 2021, 6:34pm UTC](https://forum.livingwithfibro.org/t/amino-acids-for-low-serotonin-dopamine-etc/13763 "2021-08-23T18:34:58Z")\ **Posts on this page:** 1\ **Showing post:** 6
**Author:** ![JayCS](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithfibro.org/jaycs/32/9520_2.png) [@JayCS](https://forum.livingwithfibro.org/u/JayCS)\ **Post date:** [September 10, 2021, 1:15pm UTC](https://forum.livingwithfibro.org/t/amino-acids-for-low-serotonin-dopamine-etc/13763/6 "2021-09-10T13:15:33Z")
## Rhodiola rosea seems to help amino acids - & also be anti-inflammatory Looking again at [this healthfully page](https://healthfully.com/how-to-balance-dopamine-and-serotonin-levels-5129037.html), I’m discovering more connections. What I’ve already taking note of is them pointing to 500 mg L-tyrosine and 25 mg of vitamin B6 in the _mornings_ to increase dopamine, and L-tryptophan in the _evenings_ to increase serotonin (tho the studies are old). I admit I haven’t really digested it tho. Personally, I have to watch out more for my sfx, esp. seizures. I get these if I increase dopamine, or serotonin too much, and as that was the case I shdnt be increasing either more than I have been, or watch for the balance. But what it also says (lower on the same page at the mo), with [a different URL](https://healthfully.com/448669-how-to-use-5-htp-with-rhodiola-rosea-to-keep-serotonin-for-the-brain.html), is to take 50mg of 5-HTP and also 200-600mg Rhodiola rosalea (roseroot, rosewort, Rosenwurz) for serotonin. But the latter also - referring to [drugs.com](http://drugs.com) - to increase the permeability of the Blood-Brain-Barrier, which allows precursors to serotonin and other neurotransmitters and [https://www.drugs.com/npp/rhodiola-rosea.html](https://www.drugs.com/npp/rhodiola-rosea.html), which itself refers to several studies: “_ **Depression** _ _CNS activity of R. rosea has been reported.[12](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b12) Earlier studies found that low to medium doses of the plant had stimulatory effects, while larger doses had sedative effects.[2](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b2) In lower doses, R. rosea stimulated norepinephrine, dopamine, serotonin, and nicotinic cholinergic systems in the CNS. R. rosea also increased the permeability of the blood-brain barrier to precursors of dopamine and serotonin[41](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b41), [42](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b42), [43](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b43) and improved cerebral circulation.[44](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b44) In an in vitro study, R. rosea root extract inhibited monoamine oxidases A and B.[45](https://www.drugs.com/npp/rhodiola-rosea.html#fandc-np5406.b45)_” > **These are the articles referred to, 1986-2009** > > 12: 12. Panossian A, Wagner H. Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. _Phytother Res_ . 2005;19(10):819-838.16261511 > 2. Brown RP, Gerbarg PL, Ramazanov Z. _Rhodiola rosea_ : a phytomedicinal overview. _HerbalGram_ . 2002;56:40-52. > 41. Kurkin VA, Zapesochnaya GG. Chemical composition and pharmacological properties of _Rhodiola rosea_ . _Chem Pharm J_ . 1986;20(10):1231-1244.42. Petkov VD, Yonkov D, Mosharoff A, et al. Effects of alcohol aqueous extract from _Rhodiola rosea_ L. roots on learning and memory. _Acta Physiol Pharmacol Bulg_ . 1986;12(1):3-16.375162343. Saratikov A, Marina TF, Fisanova LL. Effect of golden root extract on processes of serotonin synthesis in CNS. _J Biol Sci_ . 1978;6:142. > 44. Pogorelyĭ VE, Makarova LM. _Rhodiola rosea_ extract for prophylaxis of ischemic cerebral circulation disorder [in Russian]. _Eksp Klin Farmakol_ . 2002;65(4):19-22.1244906945. van Diermen D, Marston A, Bravo J, Reist M, Carrupt PA, Hostettmann K. Monoamine oxidase inhibition by _Rhodiola rosea_ L. roots. _J Ethnopharmacol_ . 2009;122(2):397-401.19168123 Now my doc had prescribed “rosalea” to get my blood pressure down, which it now is, altho nothing on this page mentions blood pressure. So I’m having a look for more modern studies and am pleased to find even more goodies: > **[Anti-inflammatory effects of Rhodiola rosea L.: A review - PubMed](https://pubmed.ncbi.nlm.nih.gov/31715370/)** > > Rhodiola rosea L., a worldwide botanical adaptogen, has been confirmed to possess protective effects of inflammatory injury for many diseases, including cardiovascular diseases, neurodegenerative diseases, diabetes, sepsis, and cancer. This paper is... Seems to be anti-inflammatory [Anti-inflammatory effects of Rhodiola rosea L.: A review - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0753332219329671?via%3Dihub), mainly due to the salidroside in it. > **Studies from 2021** > > [A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers - PubMed](https://pubmed.ncbi.nlm.nih.gov/33896388/) 2021: help with stress in combination. > [The Therapeutic Effects and Mechanisms of Salidroside on Cardiovascular and Metabolic Diseases: An Updated Review - PubMed](https://pubmed.ncbi.nlm.nih.gov/33991395/) 2021: Might be good. > [A supercritical fluid workflow for the quality assessment of herbal drugs and commercial preparations from Rhodiola rosea - PubMed](https://pubmed.ncbi.nlm.nih.gov/33638206/) 2021: A quick way to control the quality of the compound. > [Quality Evaluation of Randomized Controlled Trials of Rhodiola Species: A Systematic Review - PubMed](https://pubmed.ncbi.nlm.nih.gov/34306163/) 2021: Still no good trials. > (cf. [Rhodiola rosea for physical and mental fatigue: a systematic review - PubMed](https://pubmed.ncbi.nlm.nih.gov/22643043/) (2012: all trials have a high risk of bias)) > [Dietary Supplement Ingredients for Optimizing Cognitive Performance Among Healthy Adults: A Systematic Review - PubMed](https://pubmed.ncbi.nlm.nih.gov/34370563/) 2021: Better trials needed. > [Running out of time to smell the roseroots: Reviewing threats and trade in wild Rhodiola rosea L - PubMed](https://pubmed.ncbi.nlm.nih.gov/33358852/) 2021: Due to the demand & things like illegal harvesting, the real wild plant needs to be protected. --- _[View the full topic](https://forum.livingwithfibro.org/t/amino-acids-for-low-serotonin-dopamine-etc/13763)._