Fibromyalgia References: Triggers, Symptoms, Treatments - & Hunting & Tracking them

Miss everyone JayCS. In horrible flare. Mom has been in and out of hospital. Had to move her to a nursing home last week. And she’s now receiving hospice care. Lots of family drama. I’m exhausted. Didn’t want to continue complaining every time I would write something on this site. Don’t have much to give to others. Feel badly about that too. Hope to be an active participant soon. Keep up the good work my friend! (( hugs))

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@Freedom Please do not beat yourself up because you are unable to give to others. You are under an awful lot of stress with your mum being so poorly and family members. It is at these times we need the support of others and there is nothing wrong with that. There will be a time when it will be right to give out but not at the moment. Stress makes fibro so much worse - that is from experience! Praying that you will have a peaceful Christmas.

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I am having computer problems today. All the smiling faces came up wirthout me putting them in. I do not know how to get rid of them!!!

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Hehe, how nice of your computer to “blush”-smile for you, rosebud!

To edit a post you click on the “pencil” bottom right of a post you posted yourself.
(A heart for liking and the two chain-links to the left of it, and 3 dots and “Reply” to the right, see picture 1)
Only works for a few hours tho.
A new way since November: Mark what you want to change in a post, then choose right “Edit”, not left “Quote” which then appears (see picture 2) and if you’re lucky just the bit you want to edit will appear in a small window (picture 3), if not the whole post will open, maybe at exactly the right place which you’d marked.

#1:

#2:
Post - new edit 0

#3:

That said, I like them, why not leave them?! :blush::blush::blush:

Rosebud, I love the smiling faces! They made me smile! My little dog Max might have cancer. :unamused: I love him sooooooooo much. This last Monday, the vet did a needle biopsy. Should find out the result any day now. He has several swollen lymph nodes on the right side of his neck. :cry:

Maybe that’s easier for you now? Hope so.

I wrote a bit about us having to learn to “take” more, and how, the other day, that came to my mind, not sure how that fits, but I’ll post it anyway, here. (I’m sure you’re taking and also giving all you can from/to Max, and have been giving more than you can to your mom; not sure what “taking” from us here might mean, but easiest would mean you always have an open invitation to vent here, like @rosebud74 says).

Let’s hope and pray :pray: that Max has only swollen lymph nodes… and isn’t suffering too much.
:hugs: :hugs: :hugs:

Chicken or the egg causality dilemma

Before listing any of of the causes or triggers, most important is that we are in a chicken-and-egg-dilemma: Any biomarker, symptom etc. that may be present can be an effect or a cause or both, or a vicious circle.

The 2012 editorial by Ann Gardner in Nutrition “Fibromyalgia: unknown pathogenesis and a “chicken or the egg” causality dilemma” may be referring to that, a stub of which I’ve found here

stub

In this issue of Nutrition, Cordero et al. [1] describe the alleviated symptoms in a woman with fibromyalgia during treatment with coenzyme Q10. The endogenous production of Q10 decreases with age [2], thus increasing the importance of nutritional intake. Q10 has been approved by the U.S. Food and Drug Administration for the treatment of mitochondrial disease in research. The restored mitochondrial function as described by Cordero et al. [1] during Q10 treatment suggests that, in this case, mitochondrial dysfunction is likely to be the effector, and possibly even the primary, pathophysiologic mechanism. The hypothesis that mitochondrial dysfunction is involved in fibromyalgia has existed for some time, as exemplified by themention of the word mitochondria 18 times in a 10-page review article published in 2000 [3]. In an 11-page review article published in 2011, there was no mention of mitochondria [4]. Diagnosing mitochondrial disease/dysfunction is cumbersome because there is no single test that will prove or disprove an abnormality [5]. As in fibromyalgia, mitochondrial disease manifests in symptoms involving several tissues or organs and include personality and psychiatric disorders. Muscle pain is a hallmark of mitochondrial disease, but there have been only three case reports of patients with mitochondrial disease and fibromyalgia [6–8]. Three studies of psychiatric disorders in mitochondrial disease have been published, with all reporting increased prevalences, mostly depressive disorder. It has been suggested that the possibility of mitochondrial disease should be considered in patients with psychiatric disorders if other symptoms, e.g., muscle pain, are present [9–11]. Perceived stress, and neuroticism (the enduring tendency to experience negative emotional states), which has a relatively strong relation with depression, have been associated with key symptoms of fibromyalgia [12]. Neuroticism has been shown to have a moderate additive genetic component and a substantial non-shared environment component [13]. The designation “central sensitivity syndromes” has been proposed for a large continuum of disorders with epidemiologic and clinical overlaps, including fibromyalgia, tension-type headache, migraine, and irritable bowel syndrome, all of which overlap with psychiatric disorders. The current diagnostic labels for central sensitivity syndromes have been suggested to be arbitrary because there is no objective tissue pathology to which “disease” can be anchored. The unknown pathophysiology of central sensitivity syndromes underlies the construct of “somatization,” the notion that somatic

The case study that editorial refers to:
Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient. [Nutrition. 2012] here.