JayCS’s Fibro Blog

Symptoms & Treatments
705

2022-02-15, Tuesday - 15% = less than Saturday (not counting: Sunday overdoing it and Monday paying for it) and Friday, which were less than Thursday…

v2: 13:30 slightly exciting bloods… :smirk:
v1: 9:00 The antihistamine worked well tonight - still without passiflora. Felt good and good start, except not full energy. 10:10 Whoops, just realized I’ve taken a 2nd antihistamine pill, got confused with changing from mornings to evenings. Well, now I can find out if 2x10mg if the pro/con-balance is better, like one study suggests…

Triggers & resulting Symptoms

SLEEP (click for details): 8h48, up 4x (32') ✅, and ➔ Feeling 90% well, Ache 1 of 7 ✅, getting up: 90%/2 ✅, well & active, despite some Ache then. Sinuses only slightly at the beginning of the night & hardly nostrils towards the morning. Stints: 2x1h30, 30', 2h15, 2h15. Does that mean I can stop passiflora now? Or see if they work together. Or add +1=2 NAC first.

No fw! lbu: belly tensing? No half-sitting on sofa! SUPPS & AIR 1st!
cold shower p0 Sleep 23:00- A4+B1=Rupafin.
1:25 5’ 90%/1 p0 st1 drink fw2’
2:55 17’ 90%/1 p0 st1 drink fw7’ air
3:35 5’ 90%/1 p1-2! st1 drink fw2’ air
5:55 5’ 90%/1 p0 st1 drink fw2’ elbow. NO NOSTRILS. Pretty good. Cold OK.
-8:20 bit of nostrils towards the end, but not uncomfy.
Sum: 1h+8h20-(5+17+5+5=)32’ = 9h20-32’ = 8h48, up 4x (32’)

ACTIVITIES (aiming for 40% - well 20% - of pre-fibro) ➔ ACHE: ➔ Housework 80%/3, but OK. Table tennis from the end of the 2nd game on: ➔ 85%/4. After rest/fw & breath-hold: ➔ 85%/2. 13:30 tired. Rest, music, short cycle-walk & shop was pretty much ➔ 70%/3. :face_with_monocle:
"HOW DO I LOOK?" 9:00 look kaputt, so rest now :face_with_monocle: :trophy: 12:35 white-blue lips, palish face as ever, so rest again :face_with_monocle: :trophy:
ACTIONS ➔ PAINS: :white_check_mark: Bit of elbow once at night: stretches sufficed. pee pain 1-2 at 21:40 (before GABA) and 3:30, as well as 18:45 p1. GI: Big esophagus block at 15:30 :x:

Treatments

Docs:
Blood results:

  • Copper & anti-P (lupus??) not there yet.
  • Lipids sky high; but statins are a problem with antihistamines.
  • Thyroid OK except again MAK/TPO (a bit less than July 2020),
  • IgG4 still upper end, but no longer above it.
  • Other MCAS-bloods normal, but Factor VIII somewhat over the limit, bringing my score on the MCAS-questionnaire up to 24 (14’d suffice). Factor VIII might be an additional thrombosis risk for me, but aspirin like statins is also a problem with antihistamines (see ‘research’ below).
  • If I do have Anti-P, re-check alpha-fodrin for lupus (slightly increased July 2020).
  • Why increased glucose?: see research below: gut, genetics or is it chromium, should I check?

WHB (3 rounds) :one: 9:30 1’30’’ 1’50’’ 2’10’’ (in) 1’30’’ 2’30’’ (out) :trophy::trophy: :two: 1’10’’ 2’, 2’ :trophy:
RIBOSE: :one: 18:55 (should’ve tried it before cos of the fatigue)

SELF-PHYSIO (click for details): 2h46 ✅. More combinations. Temperature 36,!7°C

:white_check_mark: airing 4x2’, cream fc/ey/hd/ft 4x1’, HWB 2x3’, belly 1’, back 4’, plantar/calf stretch 3’, twist-stretch 12’, marionette-hang 1’, hand-exerciser 2’, aloe vera 1’, teeth 3x2’, breath exercises 3’, cold shower (10’), Timing, facetime 3x1’, hunchback-pillow 5’,
temperature 1x5’, hair/nails 15’, loins 2’, yoga/stretching 1’, breath-hold 19’+12’, left foot on/under right knee/cross-legged 20’+18’+5’.
Combinations
:x: calendula/tea tree x1’, AuTr 20’, palpate 1’, neck 1+ 2’, neck 2 4’, jolt-jump 1’, workout 7’, shaking dance 1’, acupressure 6’, bent leg fall 1’, horse stance 1’.
:question:: foot bath 15’, V ‘, massage gun 20’, mirror 2’, RR x2’, nux vomica 1’.

10:10 Whoops :face_with_open_eyes_and_hand_over_mouth:, just realized I’ve taken a 2nd antihistamine pill, got confused with changing from mornings to evenings. Well, now I can find out if 2x10mg if the pro/con-balance is better, like one study suggests…

Supps (Feb 12th: 31): Supp costs: ~344€/m (halved CoQ10, no Sr, re-added vit. C.+NAC; minus re-ordering some). CHANGE: ALA & pine: later(?) - increases alertness; but praps more for burning mouth? CoQ10/ubiquinone <150mg/d better for lp(a). Look for better honokiol & rhodiola. Starting arginine soon for lipids. Magnesium malate good for waking(?), so stopping evenings. RIBOSE!? PLANNED/TAKEN TODAY: click for details:

ZERO: Arg, B3/Nia, Mum, (Nd), Rib, Pe, Ps, Se, 0 Sr 0x31125k.
(REGULAR as of Feb 12th (31, except I need new Mg Gly, Pf, pine bark, Zn & will be starting Ar soon): ALA .2g, B2 2*.1g, B12 5mg/2m, C 12.5g, Cr 31g, DAO before meals, D3 1/w, EGCG 50%.5g (praps also L-theanine?) EllagicA .2g (+43mg vit. C), Fev/MSM .4g (+.2g MSM) Ga: 4*.6g+.4g=~2.8g, 3Gi, Glu:~0.8g, Hon 2%.4g=8mg, Luteolin .2g, Mg (Gly) 0250mg, Mg (Mal) 0245mg, Ω3, Nc 1.5g, P5 27mg, Pf4, pine bark 2*.5g, Pq 1, Q10 (ubq) 1*.1g/d, Qc 4*.5g/d, Rs 250%.4g, Ro 2*.2g(+B1 1.4mg (& MgCO3 60mg)), Sa .1g, Sily 80%*.5g (+83mg L-cholin) , The.2g (+.15g polyphenols), Zn 1)
What-when-details: Updated Jan 20th (before: see the reference post)
/20:00 A1/2 “19:00” 0PF#1 0Cr#1 0mal#1+2 P5P/2Rho(0Se) PQQ Ω3 & Qc. Meal: DAO.
/21:45 A3 “21:00” 0PF#2 .6 GABA&.4glu#1 & Lut (slp!) & Qc +1NAC
/ Chamomile tea.
/23:00 A4 “23:00” 0PF#3 .6 GABA&.3glu#2 & Ellagic acid
/23:00 B1 “01:00” 0PF#4 0SRP#1 + Rupafin
Heating on! Warm shower?
/8:20 B2 “07:00” +ALA+2x pine bark, (teeth)
/8:20 B3 “07:00” (-30’) Q10#1 Qc#1 Rs#1 SAM-e
/8:20 B4 “07:00” EGCg + Fev/MSM
/10:10 MEAL! C1/2 “08:00” 2Cr#2 .6GAB#3, (C2:) .1gB2, gink#1, Zn (0NAC) 1xHon! DAO?
/10:10 C3 “08:00” .5gC#1 2The2 (0NAC)
/12:50 C4 “11:00” (+2h/) gi#2 gly#1+2 0SRP#2. Nd#? & Ellagic acid
0 DAO (D1) “13:00” 0psyllium/
/16:35 D2/3 “15:00” .5gC#2,Cr#3,!.6GA#4,gink#3,0gly#3+4, 0NAC#5 DRINK!
/18:20 D4 “17:00” (“meal/acids+2h”) Qc#4.Rs#2, Nd#? 0SRP#3.
eve:
“18:00” Prepare: 1) Cpl & chk/C supp-chg. 2) Remove “v”, cut, save, paste 1x & unhide & paste 2nd (+1 to date and ##). Close 2nd TAB!
(Nov 4th, Jan 10th: B12 5mg methylcobalamin s.c.; next: Mar 10th.)

The day's 16 compartments (10', plus 5' making capsules)

Arg: Capsules? (0)Pf: A1+3+4+B1, B2:A1+C2 C:C3+D2 0x2Cr: A1+C1+D2, Ell: A4,C4. Ga: A3,A4,C1,D2, Glu: A3,a4,0D3, Gi: C2,C4,D3 0x2Gly0x2Mal: 0C4+0D3,0A2 Qc: A2.A3.B3.D4 Rs:B3,D4 SINGLE: A2:P5/Ro A3: Luteolin+NAC B2: ALA+0x2 pine B3:Sa+Q1 (->ubiquinone <150mg/d!) B4: EGCG&Fev/MSM&Sily C2:0Zn&Hon C3:2Th+Rup! (A2:Ω/Pq:meal) DAO before every meal.
(A2:0Se), (B2:0mu), (5NADH if nec.) (D1:0Pe). (0 Nia) (0Nc: A3, B1,C1,C3,D2) (0Sr: B1,C4,D4)

Development

Jab-sfx/MCAS/antihistamine: 21:40 Bladder acting up tells me it’s time for GABA. But why also at 3:30? Exhaustion-Ache most of the day, but short stints of energy, e.g. for the first game of table tennis (and won all 3 games). Praps worse after “midday meal” cos of its lateness, then the esophagus block; or from doubling the antihistamine today; of from overdoing it Sunday and down to 10% yesterday - if it’s not mid-term jab sfx then it should get better tomorrow, if it’s the jab: worse.

’Research’ today:

  • Schatzki-Ring: Recurrence does occur with rates up to 64% in the first 2 years, hence requiring repeat dilation. Schatzki Ring - StatPearls - NCBI Bookshelf
  • German woman with FM, then MCAS finds guaifenesin very helpful for FM
  • High blood sugar (glucose): exercise, carbs (sugar); gut, genetics, sugar, processed foods, grazing, dehydrated, chromium, magnesium, vit. D.. OK, so chromium would be the only thing I can influence: In this study from 2004 low chromium is connected to diabetes II, take as picolinate .2-1mg/d, it’s safe. It mentions insulin resistance, as does this Yale study from 2011 and also the results of a questionnaire of Dr. Berg which I did. The study from 2011 says chromium didn’t affect glucose, insulin or weight, but “it is possible that chromium deficient populations may respond to chromium supplementation.” (they didn’t check that) and “it is conceivable that a greater degree of insulin resistance may be required in order to detect a robust response to chromium”. So what is insulin resistance and how likely is it I tend to diabetes, something which has kept cropping up as a question for years: Quick wikipedia-looks show I have symptoms, but’d already be doing all I can aside from meds to keep it in check.
    Dr. Berg’s questionnaire attributes these symptoms to insulin resistance: cold hands and feet, fatigue, high cholesterol, loss of vitality, urinary frequency, waking up at night. Also attributes these to low cortisol (normally lowest at 2:30): chronic pain, fibromyalgia, itching, legs heavy, sinus congestion, and high (normally highest at 8:00, but in adrenal fatigue: a spike): brain chatter at night, so he attributes the wonky rhythm to adrenal fatigue and mentions the role of cortisol in allergy reactions. (As he attributes fibro and itching to low bile (= gallbladder) (and low cortisol) I’m not taking his suggestions seriously, but as something to think about and ‘research’ further, it/he also supports taking vit. C against histamine).
    A quick wikipedia-look at insulin resistance connects it to higher(?) cortisol & growth hormone, to inflammation/cytokines and to genes, and it seems to be the reason for diabetes II.
  • Alpha-fodrin: Sjögren’s AND lupus, so wait for the Anti-P result
  • Burning Mouth syndrome: possibly MCAS. Capsaicin blunts for some (my stomach can’t tolerate it tho). ALA helped in a tiny study, not reproducible, but I could try 2-3x.6g: Burning Mouth Articles by Susan E. Sklar, M.D. - Sklar Center
  • MCAS-symptoms in eyes/ears/nose/mouth, of which I have these quite a bit: dry eyes, unfocusing, noise sensitivity more, congestion, pain, burning mouth, dental decay (Ref: Afrin 2013). MCAS: Effects on eyes, ears, nose and mouth - Mast Attack
  • Factor VIII: Excess Factor VIII: A Common Cause of Hypercoagulability | American Board of Family Medicine (2005, 3 patients), in easy language, case and literature review 2019: “high factor VIII levels are an independent risk factor for thrombosis, with a greater impact on venous than on arterial thrombosis. To date, several genetic factors have been described for the variation in factor VIII levels, most importantly the ABO blood group that acts through vWF levels.”

Lessons in self-care #224 Gotta watch out, my activity is declining.
Reasons to be cheerful #231 Quite a bit of music production. Procrastinating with paper work.:smirk: