A Vicious Cycle

1. Chronic stress disrupts HPA homeostatis leading to allodynia.

2. Chronic pain disrupts the circadian rhythm.

3. Disruption of the circadian rhythm results in poor sleep.

4. Poor sleep reduces growth hormone reduction, leading to poor repair of damaged

muscle fibers, poor memory, fatigue, supressed immune system and more pain.

5. Increasd pain further disrupts sleep, and leads to the depletion of stress-coping

chemicals including serotonin.

6. A reduction in setotonin causes an increase in the neurotransmitter, substanceP.

Substance P enhances pain receptors, creating even more pain.

7. Poor sleep and on-going stress lead to fatigue, mood disorders, IBS, and may

cause thyroid dysfunction.

8. Chronic stress leads to adrenal fatigue, decreased DHEA, lowered resistance to

stress, decreased coping abilities lead to lowered immune function.

9. Lowered blood volume from adrenal dysfunction (and resultant hypotention) leads

to further fatigue. (definitions to follow)

This information was comprised by the Doctors of Douglas Labs.

HPA homeostatis- http://medical-dictionary.thefreedictionary.com/hypothalamic-pituitary-adrenal+axis

circadian rhythmhttp://www.thefreedictionary.com/circadian+rhythm


Susan, Thank you so much for sharing,alot of info I wasn't aware of. Hope you have a good day, Gemtle hugs coming your way.

WHOA. . .that's a lot. Mind if I use this list in my next fibro video?

Excellent info SK! Thanks for posting that.

Wow, that's a vicious cycle, isn't it? I had no idea that chronic pain could be so chronically disruptive to your body. It seems that the body would have an override system when it realized the chronic pain signals were stuck on "on." But no, apparently it doesn't.

This is interesting stuff, SK. Thank you for posting it so we have a bit more of an understanding of this yucky, rotten illness.

Not sure if you should credit Douglas Labs for this info or not, probably not a bad idea, I'll see if I can find that link again for you, Mo.

It would not allow me to cut, copy and paste, so lets try this


There is much more detailed info there. Douglas labs is where I purchase many of my supplements. I DO NOT SELL THEM, but my Chiropractor does, it is through him that I learned about them. I have yet to find a better Cal/Mag supplement anywhere.

I wanted to bring this back up to the main page for some of the new people to see it!

It's nice to see that your chiro sells good quality supplements instead of something expensive but so-so. I do know Douglas Labs has a good rep. for their products, and the products cost more as a result. But why buy junk?

Wish I could figure out a way to get out and stay out of this cycle. I'd have the cure of the century!

hi Sue!

I hope you're doing ok today! I want to thank you for posting that article by Douglas Labs... that was a good one ! I have seen that supplement ( the 5-HTP)...recommended before but have not tried it yet.

Now I will! The trazadone I take is great for my sleep but this sounds more natural and also might help with all my flares I've lately been having.

Peace & Blessings,


Hi Shelly,

You are correct, this is great info. This kind of info is lost on many, but I want to know everything I can get my hands on about all of this! You do need to be aware of this:


So you may want to consult your physician about his/her feelings and doseage.

It just never hurts to be safe!

I am well enough, and you?