2022-04-30, Saturday - 22% from +GABA 
-
but Ache/feverishness still high. 16:30 small focal seizure means overdose, drat… - but to tell the truth I prefer a few seizures to being able to move less… 
- but next is trying to balance it out again with glutamine and/or theanine… that’s easier done than said or thought: +.3g glutamine for starters, since I’ve taken 2x theanine at 11:35, last glutamine (.3g) was at 0:30.
I’m increasing GABA, and breath-holding; praps vit. D, praps NAC. If none of that works, back on antihistamine. Knowing that increased pee pain (yesterday) means serotonin is down I tried increasing GABA. This has greatly increased pain, energy, feeling well, as well as body “temperature”: I was freezing yesterday and cold the days before. Just gotta watch out for serotonin syndrome…
Looked serotonin and body temperature up, and YES: https://www.nih.gov/news-events/nih-research-matters/serotonin-helps-control-body-temperature-breathing (2011), or more recently Serotonin-Its Synthesis and Roles in the Healthy and the Critically Ill - PubMed (2021): In the central nervous system it acts as a neurotransmitter, controlling such brain functions as autonomic neural activity, stress response, body temperature, sleep, mood and appetite. … In its role as a peripheral hormone, serotonin is unique in controlling the functions of several organs. In the gastrointestinal tract it is important for regulating motor and secretory functions. Apart from intestinal motility, energy metabolism is regulated by both central and peripheral serotonin signaling. It also has fundamental effects on hemostasis, vascular tone, heart rate, respiratory drive, cell growth and immunity. Serotonin regulates almost all immune cells in response to inflammation, following the activation of platelets.
(Platelets? What about my increased Factor VIII? (Serotonin = “5-HT”, without the P))
Sleep 75% long, but thus restorative.
Energy (FM + MCAS) 22% (up due to GABA+)
Suppleness 90% (up due to GABA)
Alertness 100% (up due to GABA)
Feeling Well - sleep 80%, sleep breaks 70% - day 80%
Ache 30% (TT → 50%)
Local Pains 10% (various, but only short, plus plantar fasciitis in left foot since changing shoes)
MCAS (except fatigue) 10% (sinuses slightly, 15:00 more, despite the next normal GABA dose..?)
Self-treatments >1h/d (1h Yoga Nidra)
Chinese acupuncture 2.5h/wk
Triggers & resulting Symptoms
SLEEP (click for details): 11h05-1h25 = 9h40, up 6x (1h25) ✅, but ➔ Feeling 80% well, Ache 2 of 7 ✅ sleep breaks 70%/2 🧐, getting up: 80%/2 🧐 due to adding GABA, 2x.25g (+20%). 5 local pains during the night, but got all down quickly.
alternate shower p1 (despite the added GABA; but less p, so praps add bits of GABA more regularly) Sleep 22:55- air
Is %/2 before or while up? Answer: only while up, not before.
0:00 5’ 80%/2 → 70%/2 p1 st1 sip fw1’ air cream burnt tongue/mouth. A4.
0:55 5’ 80->70%->80%/2 p1 st1 sip fw1’ cream gel
2:05 5’ 80->70%->80%/2 p0 st1 sip fw1’ cream gel
4:00 15’ 80->70%->80%/2 p0 st1 sip fw10’ air cream gel stomach nauseous. .2g GABA.
5:00 50’ 80->70%->80%/2 p0 st1 sip fw10’ stomach nauseous. robin nearby waking me, as no ear plugs yet. 6. cream gel → ear plugs. Yo.Ni.10’
9:00 5’ 80%/2 p0.5 st1 sip fw1’ air cream (nostrils) (stomach nauseous) sore throat (ear plugs). Yo.Ni.
-10:00 80%/2 p0 st1 sip No nostrils, very slight sinuses, some stomach nauseous, no sore throat any more, B2-4 + GABA (whoops!) + D3.
Sum: 1h05+10-(5+5+5+15+50+5=)1h25 = 11h05-1h25 = 9h40, up 6x (1h25)
ACTIVITIES (aim: 40%) ➔ ACHE: ?70%/3
cycling 
80%/3, TT 
3:1 80%/5,
meetings/social 
, mask 
, kids 
, work ➔ ?80%/2) ?
ACTIONS ➔ PAINS: neck: stiff/hurting in bed once, needed to stretch it . GI: OK-ish jaw: good.
(e.g. lie, stand, loins, sit, arms up, neck, stiff, walk, cycle, 0xp1-2, GI, talk, mask.)
MCAS/HIT-Symptoms/Triggers/Treatments: Except lack of real energy as ever, better since GABA. Bit of sinuses tho - does that mean it’s too much GABA? 14:25 A tit-bit of walnut in a nuts & raisins mix ‘burnt’ my tongue tip again… But then the side of my tongue started burning as well, my wife discovered some injury and looking in the mirror I remembered biting on what I thought was my cheek - obviously tongue…! Testing the tongue itself
Fibro & Touch:
Covid-danger:
Treatments
Docs:
Chinese Acupuncturist - Very slightly better from #14 28th, now together with GABA which is probably balancing out its increased cortisol…
SELF-PHYSIO (click for details): yoga/stretching 5’, Y. Nidra 1h, twist-stretch 3’, plantar/calf stretch 2'
airing 6x2’, cream fc/ey/hd/ft 6x1’, breath exercises 1’, hunchback-pillow 15’,
Combine: next? RR!!
facetime 2x1’, cold shower (10’), teeth 2x2’, HWB 3’, Timing, palpate 1’, belly 3’, back 12’, horse stance 1’, aloe vera 1’, massage gun 20’, balance roll standing 5’, “cross”-legged 20’, breath-hold 12’, hair/nails 3’, neck 1+ 2’, neck 2 4’, loins 5’, jolt-jump 1’, marionette-hang 1’, workout 7’, hand-exerciser 3’, shaking dance 1’, acupressure 6’, bent leg fall 1’ (calendula/tea tree x1’).
Supps Apr 27th (~24): Supp costs:~277€/m (Apr 14th) CHANGED: ADDING GABA! 0 passiflora, but praps up again. 0 extra Ω3, theanine often 2 again now, but pine bark 1. Put on all other antihistamine supps again regularly, incl. for sleep 1 luteolin and 0 passiflora. EGCg is out atm. PLANNED/TAKEN TODAY: click for details:
ZERO now: Arg, B3/Nia, Mum, Mg Gly 50mg, Mg Mal 45mg, Nc 1*.5g, (Nd), (extra) Ω3, P-5-P, Pe, Ps, (Rib), Se, Sr 31125k, Zn.
REGULAR as of Apr 27th (24): ALA .2g, B2 2*.1g, B12 5mg/3m, C 2*.5g, Cr 31g, Cu 1x, usually 0 DAO before meals, D3 1/w, EGCG 0x(50%, incl. theanine?).5g, EllagicA .2g (+43mg vit. C), Fev .4g (+.2g MSM), Ga: 4*.6g+.4g=~2.8g, Gi 3*?, Glu:~0.8g, Hon (2%).4g=8mg, Luteolin .2g, Ω3 0x5mg, 0P5 27mg, Pf 1.35g, pine bark 1*.5g, Pq 1, Q10 (ubn) !1*.1g/d, Qc 4*.5g/d, Rs (50%) 2*.4g, Ro 2*.3g(+9mgC), Sa .1g, Sily (80%)*.5g (+83mg L-cholin) , The .2g (+.15g polyphenols).
What-when-details: Updated Feb 15th (before: see the reference post)
/19:50 A1/2 “19:00” 0PF Cr#1 0mal#1+2 0P5P (0Se) PQQ 0xΩ3 & Qc. Meal: DAO.
/20:15 A3 “21:00” 1PF#1 .6 GABA&.4glu#1 & 0Lut (slp!) & Qc +0NAC
- GABA .2g
/00:00 A4 “23:00” 0PF#3 .6 GABA&.3glu#2 & Ellagic acid + 0 Rupafin
0 B1 “01:00” 0 PF#4
/10:00 B2 “07:00” +ALA+1x pine bark, (teeth) +!Ro
/10:00 B3 “07:00” (-30’) Q10#1 Qc#1 Rs#1 SAM-e
/10:00 B4 “07:00” 0xEGCg + Fev/MSM + Sily - GABA .2g
/11:35 C1/2 “MEAL!” 2Cr#2 .6GAB#3, (C2:) .1gB2, gink#1, Cu (or Zn) 1xHon, 0 DAO
/11:35 C3 “MEAL” .5gC#1 2The2 (0NAC)+PEA
/13:30 C4 “11:00” (+2h/) gi#2 0gly#1. Nd#? & Ellagic acid
14:00 DAO (D1) “13:00” 0psyllium
/14:45 D2/3 “15:00” .5gC#2,Cr#3,!.6GA#4,gink#3,0gly#3+4, 0NAC#5 DRINK!
/19:00 D4 “17:00” (“meal/acids+2h”) Qc#4.Rs#2, Nd#? +!Ro
eve:
“18:00” Prepare: 1) Cpl & chk/C supp-chg. 2) Remove “v”, cut, save, paste 1x & unhide & paste 2nd (+1 to date and ##). Close 2nd TAB!
(Nov 4th, Jan 10th: B12 5mg methylcobalamin s.c.; last: Apr 10th.)
The day's 16 supp-compartments (10', plus 5' making capsules)
No more antihistaminey stuff for a while! (Not changing this overview for a few days, until I’m sure it’s OK.)
Pf: 0A1+1A3+0A4+0B1, B2:A1+C2 C:C3+D2 3x2Cr: A1+C1+D2, Ell: A4,C4. Ga: A3,A4,C1,D2, Glu: A3,a4 Gi: C2,C4,D3 0x2Gly0x2Mal: 0C4+0D3,0A2 Qc: A2.A3.B3.D4 Ro:B2,D4 Rs:B3,D4 SINGLE: A3: Luteolin A4: Rup! B2: ALA+2 pine B3:Sa+Q1 (->ubiquinone <150mg/d!) B4: EGCG&Fev/MSM&Sily C2:Cu(0Zn)&Hon C3:2Th+PEA (A2:Ω/Pq:meal) DAO before every meal.
(A2:0Se), (B2:0mu), (5NADH if nec.) (D1:0Pe). (0 Nia) (0Nc: A3, B1,C1,C3,D2) (0P5:A2) (0Sr: B1,C4,D4)
Development
More GABA together with the acupuncture. Discovered it a year ago, starting at .75g, overdosed it a few months later at 2.0g (serotonin syndrome), but increased a bit by upping other amino acids to 2.0g, had to up it to 2.4g due to jab-triggered MCAS-flare, and today upping to 2.8 - so have to watch closely not to overdose, but it’s helping energy, if not Ache & feverishness.
‘Research’ today: Anxiety is higher in FM, but studies vary considerably.
Lessons in self-care #291 Breath-hold - not properly yet, unbelievable, why don’t I just do it? I need to do it while doing something else. Now.
Reasons to be cheerful #295 More energy from GABA!
- My food
- 1st Jab-sfx-summary, last edit: Feb 7th.
- My blog references, e.g. abbreviations, supp chart/overview
- My “How to symptom track & trigger hunt”
- Next up…: Summaries & finishing off treatment list…